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AIDS
defining illnesses, their causes and treatment *
The many and varied diseases that can define the
AIDS syndrome: fungal infections of the lung, of the mucous membranes,
the brain, and the gut, and the degenerative changes in the
endothelial cells of blood vessels and lymphatic vessels (Kaposi
Sarcoma), occur because of an ongoing heightened production of gaseous
nitricoxide and oxygen radicals in immune cells and other cells.
The lack of glutathione in antigen presenting
cells then induces, that CD4 helper cells mature predominantly to
cells with TH2 cytokine prophile (which migrate to the bone marrow,
where they activate defences against bacteria by producing
antibodies), but only few mature to TH1 cells, which activate the
dedection and destruction of fungus and virus infected cells and of
altered cells. If this situation persists, a higher quantity of
proteins of the cytoskeleton and of mitochondria is released as en
effect of heightened
cell decay. Against these proteins a higher rate of the antibodies are
formed. This antibodies and antibodies that occure in hepatitis and
due to toxic pollution are detected by the HIV-antibody tests. Once a
certain, arbitrary level is reached, the patient is declared "HIV
positive".
A elevated level of nitricoxide
and oxygen radicals comes about as a result of:
ongoing contact with antigens (e.g. from
repeated or chronic infections, injuries, operations and dirty
water).
- repeated contact of foreign proteins to the
plasma (from coagulation proteins in blood preparations and from
semen liquid in unprotected anal intercourse)
- contact to toxic substances in food (e.g.
aphlatoxines in wet cereals), medicaments and from environment
pollution, toxic decomposition products from modern chemicals and
heavy metals (e.g. carrier substances in hepatitis B-vaccines,
amalgan fillings)
- inhalation of nitrites ("poppers")
which are stored in cells as NO2. They are released through
physical exertion on increased exposure to calcium ions. This
affects the endothelial cells of blood vessels and lymphatic
vessels with a small capillary diameter, and leads thereby to
degenerative changes (swollen lymph nodes and finally to Kaposi
Sarcoma).
- impairment of the mitochondria, the single
cell energy suppliers, which synthesize the
energy-carrying-molecule ATP, used for all functions of the
organism
The causes of chronic
mitochondrial damage are:
damage of the mitochondrial DNA due to
antibiotics (e.g. sulpha compounds such as Septrime, TMPSMX) which
block the synthetisation of folic acid and purine, and lead thereby
to the exhaustion of the mitochondrial thiol-pool. Likely effects
are caused by heavy metals and by cytostatics like AZT. All this
substances bind the SH-groups of glutathione and cysteine and impair
thereby the activity of mitochondria.
- reduced glutathione produced resulting from
liver damage, e.g. chronic hepatitis (occuring frequently in gay
men, hemophiliacs and intravenuous drug consumers), excessive
alcohol consumption, or through shortage of nutritional cysteine,
esp. in developing countries. Glutathion molecules reduce oxygen-
and nitricoxydemolecules, so that ATP production in mitochondria
is not disturbed. An ongoing shortage of glutathione means that
phagozyte poison themselves attacking fungi and virus containing
cells by means of NO.
- reduced oxygen transport in cells because of
oxidation (methhaemoglobinaemia) which exceeds the reductive
capacity of glutathione. This comes about because of the strongly
oxidising effect of nitrites (poppers), antibiotics (Septrime,
TMPSMX) and insecticides (e.g. Lindan in moistures against crab
louse), nucleoside analogues (e.g. AZT), heavy metals and
chemicals.
- lack of plant antioxidants which bind to
toxic degradation products (oxygen radicals) and thereby reduce
inflammation and stressreactions.
On prolonged impairment of mitochondria, they
dissolve their symbiosis with the host ("Warburg
Phenomenon"). Cells then increasingly switch over to producing
energy by anaerobic fermentation, which results in excess lactic acid
production, and the growth of fungi and opportunists, and ultimately
to wasting, at which point cells obtain essential nutrients directly
from the myoproteine. By an heightened activity of reverse
transcription the cellnucleus then saves its genotype. Continuous
activation of macrophages leads in this situation to an ongoing
release of messanger substances (Inteleukine 2) which trigger the
release of stress-hormones
in the adrenal gland. This hormones induce the formation of TH2 CD-4
cells, that activate the formation of antibodies in the bone marrow,
whereas cellular immune reactions induced by TH1 cells are
continuously suppressed.
HIV, which is held to be responsible for causing
30 different AIDS-defining diseases, has never been shown to be
transmissible nor self-reproducing; it has never been isolated,
photographed or otherwise properly characterised, as required by the
established rules of virology.
The original experimental technique of Gallo and
Montagnier in 1984 on which the HIV-antibody-tests were constructed,
involved co-culturing cells from AIDS patients with leucaemic cells
and embryonal cells, that show a high activity of reverse
transcription.
This effect of an artificially amplified reverse
transcription was then interpreted as signifying the presence a new
virus. A virus-specific enzyme could not be aprooved.
Synthetic protease inhibitors, which are
supposed to inhibit the formation of essential "viral paricles",
over time, cause malaise, diabetes, kidney stones and liver failure in
patients given them. After PIs and nucleoside analogues are first
given, an apparent decline in inflammatroy reactions and „virus
production" may be observed, but it then rises again, which is
attributed to resistance developping.
Nucleoside analog drugs, that block
for a limited time the formation of DNA bacteries and fungy, are
practicaly not incorporated into the cell nucleus, where they should
work as DNA terminators against HIV. As it has been demonstrated by
vairous animal trials since 1990 they cause irreversible damage to the
mitochondrial DNA and thereby damage to the brain, the bone marrow,
the muscles and internal organs and also a lasting decrease of CD-4
and CD-8 cells, that induces opportunistic infections (cytomegalie,
herpes simplex, PCP and toxoplasmosis), that define the AIDS-syndrome.
By means of:
A supply of sulphur compounds in sea salt,
mineral water and algal products, and of cysteine and methionine
containing protein mixtures, (Cysteine, N-acetyl-cysteine (3-8
gramme daily)and arginin also in curd and whey (or derivates:
Immunocal, HMS-90) and folic acid (300 miligramme daily) can
stimulate glutathione formation in the liver.
Plant antioxidants, e.g. PADMA 28 (2-3 times 2
tabletts daily) or artemisia annua in UWEMBA pastilles (available
from www.nusag.com) which bind to toxic oxygen decay products, and
natural protease inhibitors (heparine and heparinoids in agar,
algae, Guar or cartilage preparations), which activate the body's
own anti-proteases and bind to cations that attack the cell walls,
thereby slowing down chronic inflammatory reactions going allong
with increased cell division.
Essential fatty acids in linseed oil, (thistle
oil, soya oil)5-6 tablespoons daily)mixed with curd, can enhighten
the uptake of oxygen in cells
Co-enzyme Q10 and NADH and high doses of
Vitamin C and E can improve electron transport in the respiratory
chain of cells. Folic acid (300 milligramme daily), thiols L-carnitin
(6 grammes daily for 14 days) and low doses of selenium (250
microgrammes daily also in brewers' yeast), and zinc can support the
synthetisation of ATP in mitochondria and the repair of damage to
mitochondrial DNA.
Opportunistic infections (fungy, PCP and others
can be treated by omega-3 fatty acids in fishoil (3 tablespoons
daily) In dificult cases gamma globulin, selective cyclo-oxygenese-2
inhibitors and difluoromethylornithine as a polyamine inhibitor can
be administrated.
If vasting occurs the activity of killer cells
and neutrophillia can be supported by the administration of
glutamine (40 grammes daily) and L-Arginin (20-30 grammes daily).
Then cysteine can be administrated intravenously
untill the synthetisation of glutathione in the liver works again.
DHEAS (200 milligrammes daily) can diminish
ongoing stress reactions in the immune system (TH1-TH2-switch)
caused by the release of stresshormones (cortisol) in the adrenal
gland.
Hebral medicaments (milk thistle) to support
the liver function and partly fermented beverages (pro biotics) that
can restore the gut flora
Ethereal oils, rubbed on to the chest and in
the armpits serve to stimulate the immune system through the matrix
Extract of grape fruit kernels, gargling with
honey/vinegar and sulphur containing moistures or tea-tree oil as a
local treatment against fungal infection.
Targeted stress reduction techniques, e.g.
autogenic training, stretching and massages, and refraining from
excesive physical exercise (using perfomance-enhancing drugs, e.g.
coffee, alcohol, nicotine, amphetamines (X-tasy), cocaine, heroin
and poppers.)
avoiding inflammatory reactions and infections
by avoiding injuries and the contact of foreing proteins to the
plasma (e.g. by protection in anal intercourse).
of a nourishment poor in sugar amd acid but
rich in roughage, fiber and bases, with much high-value
carbohydrates (whole grain bread and pasta and potatoe, plant
antioxidants, e.g. vegetables, fruit, herbal and green teas,
cold-pressed oils, partly fermented dairyproducts, algae, soya
beans, and fish but not iron-rich red meat.
......a flexible resistance in
people with AIDS defining illnesses can be restored.
If limited administration of
antibiotics is necessary, this basic therapy has to be continued. The
treatment can be adapted to the individual illnesses occuring.
Progress achieved by these measures to bolster the immune system can
be monitored by measuring stress hormone profiles, the T4/T8 cell
ratio, macrophage activation (neopterine test) and cutaneous anergy,
the glutathione level in plasma and in T-4 helper cells.
Abstracts
of the used studies and articles
Study Group for AIDS therapy c/o
Felix A. de Fries
Eglistr. 7 CH-8004 Zürich
Tel./FAX:
0041 1 401 34 24
e-mail: felix.defries@bluewin.ch
* (Treatment
recommendations based on the works of Dr. Heinrich Kremer, Hamburg,
Prof. Alfred Hässig, Berne), Dr. Stefan Lanka (Suttgart) and Eleni
Papadopulos-Eleopulos (Royal Hospital, Perth) available at www.virusmyth.com
and www.continuummagazine.org and works of L. A. Herzenberg,
J.D. Peterson and S.C. De Rosa (Stanford University) and ofFurchgott
and Ignarro available at www.ncbi.nlm.nih.gov
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